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KMID : 1164220180300010153
Journal of Korean Society for Radiotherapeutic Technology
2018 Volume.30 No. 1 p.153 ~ p.160
The dosimetric guide of treatment modalities for Left side breast irradiation after conservative surgery
Kim Tae-Min

Moon Sung-Kong
Kim Li-Zzy
Kim Se-Young
Park Ryeung-Hwang
Kim Joo-Ho
Cho Jung-Heui
Abstract
Purpose : We retrospectively analyzed doses of each radiation therapy technique used in the treatment for left breast cancer patients after partial mastectomy through dose results for normalorgans and tumor volume to use this as a clinical reference for radiation therapy of domestic left breast cancer patients.

Materials and Methods : 40 patients who underwent partial mastectomy on left breast cancer were classified in 3 treatment methods. The treatment plan was evaluated by HI(homogeneity index), D95 %, and CI(conformity index), and the Vhot for gross tumor volume and clinical target volume of each treatment method. In Cyberknife treatment, tumor volume was the same as high dose volume in the other techniques, so no consideration was given to clinical target volume. Treatment plan evaluation for normal organs were evaluated by mean dose on ipsilateral lung, heart, left anterior descending artery, opposite breast and lung, and non-target tissue.

Result : Treatment with volumetric arc radiotherapy(VMAT) showed 95.84¡¾0.75 % of D95 % on the clinical target volume, significantly higher than that of 3D-CRT. The D95 % value of the total tumor volume was slightly higher than the other treatments. In Cyberknife treatment, the dose to the normal organs was significantly lower than other treatments. Overall, the maximum dose and mean dose to the heart were 26.2¡¾6.12 Gy and 1.88¡¾0.2 Gy in VMAT treatment and 20.25¡¾9.35 Gy and 1.04¡¾0.19 Gy in 3D-CRT therapy, respectively.

Conclusion : In comparison on 3D-CRT and VMAT, most of the dosimetric parameters for the evaluation of the treatment plan showed similar values, so that there is no significant difference in treatment plan evaluation. It is possible to select the treatment method according to the patient¡¯s anatomical structure or possibility of breath control. Cyberknife treatment is very useful treatment for normal organs because of its accurate dose exposure to the tumor volume However, it has restrictions to treat the local area, to have relatively long treatment time and to involve invasive procedure.
KEYWORD
breast cancer, DIBH, VMAT, Cyberknife
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